Consider the prompt below. Compose a reply and post that to the discussion. You will be able to view classmates' responses to this same prompt after you submit. There is no requirement to reply to a classmate's post!
Discussion Prompt:
Black Widow Spider Latrotoxin is a compound produced by spiders in the genus Latrodectus (such as black widow spiders). Latrotoxin creates tiny holes in cell membranes at axon terminals that allow small hydrophilic particles to pass through the membrane. Consider the above information and what we have learned thus far about activities in the neuromuscular junction.
What impacts would latrotoxin have on your muscles?
Discuss ACh, sodium, and calcium in your explanation.
Latrotoxin effects affect cell membrane which sodium and calcium currents depolarize the membrane that allow influx of sodium and calcium ions .
Increase calcium ion [Ca2+] ion resulting in increase release ACH . Excessive release of acetylcholine (ACH) at the neuromuscular junction, resulting in increase muscle contraction of skeletal muscle and cardiac muscle.
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