Scientist spot light 8

After reading the article, I have learned that Duchenne muscular dystrophy (DMD) is a genetic disorder causing progressive skeletal muscle degeneration. It is a scary progressive genetic disorder. After finding out more information on DMD that disease that disease not only affects musculoskeletal system but also affect weakening of the heart muscle.
             Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene which found in skeletal muscles (used for movement) and heart (cardiac) muscle. The dystrophin gene is located on the X chromosome. Dystrophin is important for maintaining muscle cell integrity and function for our body. I have learned that DMD, the mutated gene, fails to produce functional dystrophin that caused dystrophin’s absence resulting in muscle damage, inflammation, and progressive weakness. The mutation prevents the production of dystrophin, a protein vital for muscle strength and function.I understand that dystrophin gene mutations is essential for managing DMD and developing potential therapies. I hope that the scientist find the effective treatment for gene and cell therapies treating DMD in the future.

                     Another thing I am wondering that how Duchenne muscular dystrophy (DMD) is relationship with fibrosis. I have learned that the absence of functional dystrophin protein disrupts muscle cell integrity. DMD affects skeletal muscle degeneration. Inflammatory cells infiltrate muscle tissue. Fibrosis (scar tissue formation) significantly contributes to muscle dysfunction. Scar tissue formation impairs muscle function and limits regeneration.