Sarin is a potent nerve agent used as a chemical weapon.  It is highly lethal, even at small concentrations, causing death in only a few minutes.  Sarin was outlawed as a "weapon of mass destruction" in 1993 as part of the UN Chemical Weapons convention.  Sadly, reports of sarin use continue, with most recent concerns centering around incidents in the Syrian civil war.  Sarin works by inhibiting the activity of acetylcholinesterase.

How do you think sarin would impact the muscles?

How could you justify those predicted impacts based on the chemical interactions at the neuromuscular junction?
Resources & Reminders

If desired, you could re-watch the video at this address (https://www.youtube.com/watch?v=8Hu5W_tFXLs) and review your book

Links to an external site., paying special attention to the role of acetylcholinesterase.

Consider specifically...

    Based on the information above, which parts of the video/book description would be most directly affected by sarin?
    What are the normal roles of those parts in muscle stimulation?
    What would happen differently in the presence of sarin and why?