Saturday, March 16, 2024

When Ca2+ binds to troponin and causes tropomyosin to shift?


Troponin C - an overview | ScienceDirect Topics


(a) In the absence of Ca2+, tropomyosin prevents the binding of myosin heads to actin. 

(b) When the [Ca2+] rises, Ca2+ binds to a subunit of troponin, which causes the tropomyosin to shift slightly into the groove of the actin filament. 

The shift in position of tropomyosin allows the myosin heads to bind to actin.

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