The molecular mechanisms underlying skin wrinkling result from a substantial
deterioration of the skin matrix molecules, i.e. diminished and disorganized
collagen and reduced and distorted elastic fibers.
Collagen is the most abundant extracellular matrix (ECM) protein generated
by dermal fibroblasts.
MB treatment increases collagen in the dermis .
Elastin, the second most abundant
ECM component, is a fibrous protein that contributes to 2~4% of the dry
weight of the dermis. It provides natural elasticity and strength to human skin
and also plays a role in tissue repair
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