Monday, February 26, 2024



Deviation From  Normal : Low level of Vitamin D

Receptor                         : Bone Cell

Control Center               :parathyroid gland

Efferent Pathway           :parathyroid hormone (effects on bone because of inhibition production of hormone)

Effector                          :Stimulating Osteoclasts and inhibiting  Osteoblasts

Response                       : When blood calcium levels are low, parathyroid hormone (PTH)is released, PTH stimulates osteoclasts , also PTH inhibits  osteoblasts.Osteoclasts break down bone tissue, releasing calcium into the bloodstream.PTH also inhibits osteoblasts, which are cells involved in bone deposition. By reducing calcium deposition in bone leading not enough calcium, our bones become more fragile, leading to osteoporosis.

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