Aging is still something of a mysterious process from an anatomy and physiology perspective, but it is a fascinating one to explore! View the video below for an overview of what physiologists currently think about aging (or copy and paste this address: https://www.youtube.com/watch?v=GASaqPv0t0g)
Afterward, compose a brief reflection (approximately 4-5 sentences) on...
What were some of the main themes from the video in terms of physiological changes that happen during aging?
After watching video, I realized that health and aging depend on what we eat especially contain ultra-processed foods in our daily life. The physiological changes that happen during aging caused by GM foods that we consume every day which interacts harmful effects to our body.
What confusions or questions come up for you after this video?
It came across into my mind that how can I prevent from aging. Mitochondria produce ATP which play important role and cellular process. I am wondering how I can maintain mitochondria healthy and prevent from deterioration.
What do you already know about what happens to the skin in aging?
The sun's ultraviolet light can cause major damage to the skin related to aging. Eating ultra-processed foods also another reason that leading speed up the aging of body cells. Consume lots of trans fats and can promote the chronic inflammation that hastens the breakdown the body cells lead to aging. Consuming GM foods that caused harmful effects on the human body including DNA damage result in mitochondrial dysfunction. If all cells in the body lost their mitochondria, the cells, tissues and eventually organs inability to operate because it cannot produce energy for cell.
1997
112 years
oldest person in earth
human are build
90 years capacity
age- growing up
others growing old
scientific definition of aging
interaction with sunlight - The sun's ultraviolet light can cause major damage to the skin. The outer layer of the skin has cells that contain the pigment melanin. Melanin protects skin from the sun's ultraviolet rays. These can burn the skin and reduce its elasticity, leading to premature aging.
air ,
How aging interaction with diet -Research shows that eating ultra-processed foods can speed up the aging of your cells.
Much of this is due to ultra-processed foods often containing a high amount of hydrogenated oils, which are full of trans fats and can promote the chronic inflammation that hastens the breakdown (or aging) of your cells.
structure and function of the molecule of the cell.
recently 9 physiological treats
1 - body genetic damage -DNA damage can also result in mitochondrial dysfunction, impaired autophagy, metabolic changes, and the triggering of cellular senescence (small circles). These live but physiologically altered cells are predicted to be a more potent driver of aging and disease.
2 DNA replicate -DNA Replication Stress and Aging
Replication stress may lead to genomic instability, aging, and cancer. Genomic instability may increase during aging due to replication pausing and stalling. Generally, different forms of DNA damage and DNA breakage increase in pausing/stalling of replication.
mitochondria produce ATP (adenosine triphosphate). Main energy for all cellular process.
program cell death.
mitochondria dead -Mitochondrial biogenesis declines with age due to alterations in mitochondrial dynamics and inhibition of mitophagy, an autophagy process that removes dysfunctional mitochondria.
Age-dependent abnormalities in mitochondrial quality control further weaken and impair mitochondrial function.
epi- genetic
older people -Alzheimer's
harmful genetic alteration -causes: The biggest threat caused by GM foods is that they can have harmful effects on the human body.
It is believed that consumption of these genetically engineered foods can cause the development of diseases which are immune to antibiotics.
What are GMOs?
Genetically Modified Organisms (GMOs) are created through the process of genetic engineering: a technology that takes DNA from one organism and moves it into another, creating new varieties of plants and animals that wouldn’t be found in nature.
Organic is non-GMO because the use of GMOs is prohibited in organic production. For example, organic farmers cannot plant GMO seeds, organic livestock cannot eat GMO feed, and organic food manufacturers cannot use GMO ingredients.
What GMO crops are in the United States?
Corn: Corn is the most commonly grown crop in the United States, and most of it is GMO. ...
Soybean:
Cotton: ...
Potato: ...
Papaya: ...
Summer Squash: ...
Canola: ...
Alfalfa:
decline as we age.
package with chromosome!
telomer become too short - process that halt cycle.
cancer proliferation
cutting short to replicate
resize - without limit to other cells.
other changes revolved
stop being able to do
toxic nutrients
intercellular communication
aging
longer life we know it
exercise
medicine
gene therapy
live longer we already do
no tell
how can you prevent mitochondria dead?
Clinical trials have shown the utility of using oral replacement supplements, such as l-carnitine, alpha-lipoic acid (α-lipoic acid [1,2-dithiolane-3-pentanoic acid]), coenzyme Q10 (CoQ10 [ubiquinone]), reduced nicotinamide adenine dinucleotide (NADH), membrane phospholipids, and other supplements.
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